Plot no 105, Part A, Karnataka Industrial Area Development Board, Humnabad, Karnataka 585330
Chemical Structure of 1,2,3,9-Tetrahydro-4H-carbazol-4-one

1,2,3,9-Tetrahydrocarbazolone (Carbazolone)

CAS No: 15128-52-6

A high-purity carbazole derivative (commonly known as 1,2,3,9-tetrahydro-4H-carbazol-4-one, 4-Oxo-1,2,3,4-tetrahydrocarbazole, or 1,2,3,4-Tetrahydrocarbazol-4-one) essential for the synthesis of complex pharmaceutical compounds.

This compound is widely utilized as a key starting material (KSM) in the manufacturing of Ondansetron (anti-emetic) and Carvedilol (beta-blocker). Kalpasthana Life Care Products ensures premium purity standards for this intermediate.

Product Specifications

Product Name 1,2,3,9-Tetrahydrocarbazolone
Synonyms / Abbreviations 1,2,3,9-Tetrahydro-4H-carbazol-4-one, Carbazolone, 4-Oxo-1,2,3,4-tetrahydrocarbazole, 1,2,3,4-Tetrahydrocarbazol-4-one
CAS Number 15128-52-6
Molecular Formula C12H11NO
Molecular Weight 185.22 g/mol
Appearance Off-white to Pale Yellow Powder
Purity (HPLC) ≥ 99.0%
Melting Point 220°C - 225°C

Applications & Usage

This compound is a dual-use pharmaceutical intermediate. It is critical for synthesizing Ondansetron (used in chemotherapy support) and serves as a precursor for Carvedilol, a vital drug for managing hypertension and heart failure.

Key Features
  • Dual Application: Supports manufacturing lines for both anti-emetic and cardiovascular drugs.
  • High Stability: Manufactured to ensure long-term stability under proper storage conditions.
  • Bulk Capacity: Available in commercial quantities from our Humnabad facility.

Product Specifications & Procurement FAQs

Detailed quality specifications, compliance data, and procurement answers for pharma sourcing professionals.

Quality & Technical Specifications

Chemical Synonyms Tetrahydrocarbazolone, 1,2,3,9-tetrahydro-carbazol-4-one, Ondansetron precursor, Carvedilol precursor
Manufacturing Location Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330
Compliance & Quality GMP-compliant state-of-the-art facility, rigorous HPLC purity standards ≥99.0%.
Commercial Packaging Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.

Frequently Asked Questions

What is the primary role of 1,2,3,9-Tetrahydrocarbazol-4-one (CAS 15128-52-6) in API manufacturing?

1,2,3,9-Tetrahydrocarbazol-4-one (often referred to as Tetrahydrocarbazolone) is a critical dual-use pharmaceutical intermediate. It is most notably utilized as a key precursor in the synthesis of the anti-emetic drug Ondansetron (Zofran) and the anti-hypertensive agent Carvedilol. Sourcing a high-purity intermediate is crucial to optimize downstream reaction yields and minimize process impurities.

What are the specifications and quality compliance standards for bulk sourcing of 1,2,3,9-Tetrahydrocarbazol-4-one?

Our commercial-grade 1,2,3,9-Tetrahydrocarbazol-4-one is manufactured under strict quality controls, maintaining an HPLC purity of ≥99.0%. We provide complete regulatory documentation for B2B compliance, including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), gas chromatography profiles, and impurity reports.

What are the packaging, storage guidelines, and transport logistics for bulk Tetrahydrocarbazolone?

The standard bulk commercial packaging for 1,2,3,9-Tetrahydrocarbazol-4-one is 25 kg HDPE fiber drums with double sealed polythene inner liners. It should be stored in a cool, dry, well-ventilated warehouse away from strong oxidizing agents. Kalpasthana handles worldwide logistics with certified hazardous material transport compliance.

Chat with us!